Staff profile

• 3D cell culture
• Pluripotent Stem Cells
• Senotherapeutics
• Skin Ageing
• Stem Cell Differentiation

Journal Article

• Low, E., Smith, L. A., Miwa, S., Fielder, E., Przyborski, S., & von Zglinicki, T. (2025). Senescent Dermal Fibroblasts Decrease Stemness in Basal Keratinocytes in a Bioengineered Model of Human Full-Thickness Skin. Journal of Investigative Dermatology, 145(1), 208-211.e8. https://doi.org/10.1016/j.jid.2024.07.004
• Smith, L., Quelch-Cliffe, R., Liu, F., Aguilar, A. H., & Przyborski, S. (online). Evaluating Strategies to Assess the Differentiation Potential of Human Pluripotent Stem Cells: A Review, Analysis and Call for Innovation. Stem Cell Reviews and Reports, https://doi.org/10.1007/s12015-024-10793-5
• Goncalves, K., De Los Santos Gomez, P., Costello, L., Smith, L., Mead, H., Simpson, A., & Przyborski, S. (2023). Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent. Bioengineering and Translational Medicine, 8(2), Article e10415. https://doi.org/10.1002/btm2.10415
• Hidalgo Aguilar, A., Smith, L., Owens, D., Quelch, R., & Przyborski, S. (2022). Recreating Tissue Structures Representative of Teratomas In Vitro Using a Combination of 3D Cell Culture Technology and Human Embryonic Stem Cells. Bioengineering, 9(5), Article 185. https://doi.org/10.3390/bioengineering9050185
• Low, E., Alimohammadiha, G., Smith, L. A., Costello, L. F., Przyborski, S. A., von Zglinicki, T., & Miwa, S. (2021). How good is the evidence that cellular senescence causes skin ageing?. Ageing Research Reviews, 71, https://doi.org/10.1016/j.arr.2021.101456
• Smith, L., Hidalgo Aguilar, A., Owens, D., Quelch, R., Knight, E., & Przyborski, S. (2021). Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts. Frontiers in Cell and Developmental Biology, 9, https://doi.org/10.3389/fcell.2021.667246
• Hoyle, H., Smith, L., Williams, R., & Przyborski, S. (2020). Applications of novel bioreactor technology to enhance the viability and function of cultured cells and tissues. Interface Focus, 10(2), Article 20190090. https://doi.org/10.1098/rsfs.2019.0090