Staff profile

Journal Article

• Arbitrium phages can manipulate each other's lysis/lysogeny decisions.
  
  Manley, R., Woodhams, R., Arrowsmith, T. J., Smith, E., Bruce, J., Blower, T. R., Temperton, B., & Westra, E. R. (2026). Arbitrium phages can manipulate each other’s lysis/lysogeny decisions. Cell. Advance online publication. https://doi.org/10.1016/j.cell.2026.02.020
• tRNAs as toxin targets in phage defence and a focus of counter-defence against abortive infection.
  
  Arrowsmith, T. J., Puiu, M., & Blower, T. R. (2026). tRNAs as toxin targets in phage defence and a focus of counter-defence against abortive infection. Current Opinion in Microbiology, 89, Article 102697. https://doi.org/10.1016/j.mib.2025.102697
• Ribonuclease toxin RelE1 inhibits growth of Mycobacterium tuberculosis through specific cleavage of the ribosomal anti-Shine–Dalgarno region
  
  Han, X., Beck, I. N., Mansour, M., Arrowsmith, T. J., Barriot, R., Chansigaud, P., Pagès, C., Hamze, H., Akarsu, H., Falquet, L., Redder, P., Xu, X., Blower, T. R., & Genevaux, P. (2025). Ribonuclease toxin RelE1 inhibits growth of Mycobacterium tuberculosis through specific cleavage of the ribosomal anti-Shine–Dalgarno region. Nucleic Acids Research, 53(21), Article gkaf1070. https://doi.org/10.1093/nar/gkaf1070
• Nucleotidyltransferase toxin MenT extends aminoacyl acceptor ends of serine tRNAs to control Mycobacterium tuberculosis growth
  
  Xu, X., Barriot, R., Voisin, B., Arrowsmith, T. J., Usher, B., Gutierrez, C., Han, X., Pagès, C., Redder, P., Blower, T. R., Neyrolles, O., & Genevaux, P. (2024). Nucleotidyltransferase toxin MenT extends aminoacyl acceptor ends of serine tRNAs to control Mycobacterium tuberculosis growth. Nature Communications, 15(1), Article 9596. https://doi.org/10.1038/s41467-024-53931-w
• Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins
  
  Arrowsmith, T. J., Xu, X., Xu, S., Usher, B., Stokes, P., Guest, M., Bronowska, A. K., Genevaux, P., & Blower, T. R. (2024). Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins. Nature Communications, 15(1), Article 7719. https://doi.org/10.1038/s41467-024-51934-1
• MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding
  
  Xu, X., Usher, B., Gutierrez, C., Barriot, R., Arrowsmith, T. J., Han, X., Redder, P., Neyrolles, O., Blower, T. R., & Genevaux, P. (2023). MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding. Nature Communications, 14, Article 4644. https://doi.org/10.1038/s41467-023-40264-3